Research foundation · 2023–2026

DNA Microfactory for Autonomous Archiving.

The DNAMIC startup grew out of a three-year EIC Pathfinder research project, coordinated by UAB Genomika with a consortium of partners across the EU, Switzerland and the UK, and embedded in DigNA — the European portfolio of nine DNA data-storage projects. This page preserves the project's public record and the ecosystem around it, as the startup takes over the brand and continues the work commercially.

The project

We live in a society that produces and requires more and more data every year — yet current data-storage strategies are not adequate for long-term preservation. The DNAMIC Pathfinder project proposed an autonomous solution built around a low-energy-consumption microfactory for end-to-end DNA-based data archiving: from encoding to decoding via synthesis, storage, quality control and sequencing.

The microfactory is interoperable and future-proof thanks to technology blocks that can be modified or replaced. The solution is compliant with the Open Archival Information System (OAIS) reference model (ISO 14721). To enable disaster recovery — critical for long-term storage — the project developed a novel encoding scheme that produces self-contained data fragments resilient to strand-level loss.

Over three years the consortium built the codec, synthesis chemistry, encapsulation, reader automation, and the integration with the OLOS long-term preservation system that now form the core of the DNAMIC commercial product. The Pathfinder project ended in September 2026; the startup, a Genomika spin-out, carries the technology and team forward.

Workpackages

The consortium organised three years of work into six workpackages. Each carried a specific objective and a lead partner, feeding into the integrated microfactory and its dissemination.

WP1

Management

Define the organisation and provide the structure to communicate within the consortium and with external stakeholders. Maintain the tools and methods to keep track of progress and attain contractual objectives including reporting.

WP2

Architecture

Define the overall system architecture, including the data and process flows. Validate the end-to-end solution with real-world data.

WP3

Optimised writing & reading

Develop universal encoding strategies to optimise the write process and minimise the storage space (number of nucleotides) used. Improve readout through sequencing optimisation.

WP4

Microfactory and sample processing

Develop and optimise the microfactory for DNA processing and manipulation, including the smart pipette and its integration. Develop and integrate autonomous synthesis, preparation and sequencing steps. Integrate within the OLOS long-term preservation system.

WP5

Exploitation and dissemination

Cover dissemination (website, publications, public relations, open science, Data Management Plan) and exploitation (IP, stakeholder meetings and interface).

WP6

Portfolio activities

Strengthen prospects for successful completion and the initial steps toward market by developing synergies and collaborations with the other projects funded under the 2022 EIC Pathfinder challenge on DNA-based digital data storage — the DigNA portfolio.

DigNA — the European DNA data-storage portfolio

DigNA is the umbrella name for the nine projects funded under the 2022 EIC Pathfinder Challenge on "DNA-based digital data storage". The challenge sought scalable, reliable approaches to DNA as a data-storage medium — improving read, write and edit operations, exploring alternative coding techniques and polymeric substrates, and pushing throughput, length, reliability, speed and cost well beyond the state of the art. DNAMIC is one of the nine.

Portfolio projects

DNAMICOur project

DNA Microfactory for Autonomous Archiving

End-to-end automated microfactory: codec, proprietary synthesis, encapsulation, retrieval and reading for long-term archival. Coordinated by Genomika.

PEARL-DNA

Interoperable end-to-end platform

Scalable, sustainable, high-throughput technologies spanning the full DNA data-storage pipeline.

DiDAX

Computational, chemical & biotech solutions

Improved DNA data storage via in-product information, cryptography and long-term archiving approaches.

DISCO

DNA-based infrastructure for storage and computation

Joining storage and in-molecule computation into a single infrastructure stack.

Dura-store

Dynamic, ultra-stable, random-access RNA retrieval

Exploring RNA as the carrier for fast random-access molecular storage.

MIDNA

Microbe-synthesised DNA nanostructures

Display-controlled storage cartridges built from biologically produced DNA nanostructures.

HYPERION

Enzymatic DNA synthesis on CMOS chips

Affordable, scalable DNA writing through a very dense semiconductor integrated circuit.

NEO DNA

Next-generation molecular data storage

Novel writing and reading chemistries targeting a step-change in molecular storage performance.

TEXTA-DNA

Text storage & retrieval in encapsulated nanofibres

High-throughput oligo synthesis and NGS for text-scale digital storage in DNA-bearing nanofibre capsules.

Cross-portfolio working groups

To structure and intensify collaboration across the portfolio, four working groups were created. DNAMIC partners participate in all four.

WG1 Technical synergies WG2 Outreach & public engagement WG3 Metrics, standards & roadmapping WG4 IP protection & exploitation

Consortium

Eight partners across five countries contributed to DNAMIC — coordinated by Genomika, with academic and industrial participants and associated partners in Switzerland and the United Kingdom, covering codec, chemistry, hardware, and archival integration.

Project coordinator

UAB Genomika Lithuania
linkedin.com/company/genomika-lietuva

Project partners

Kaunas University of Technology Lithuania
ktu.edu
Technical University of Munich Germany
tum.de
Kilobaser / MABEAL GmbH Austria
kilobaser.com
Helices Biological Photolithography GmbH Austria

Associated partners

Haute École Spécialisée de Suisse occidentale Switzerland
hes-so.ch
Université de Genève Switzerland
unige.ch
Imperial College London United Kingdom
imperial.ac.uk